Impact of psychological problems in chemical warfare survivors with severe ophthalmologic complication,across sectional study

Gholam hosein Ghaedi1, Hassan Ghasemi, Batool Mousavi, MohammadReza Soroush, Parvin Rahnama, Farhad Jafari, Siamak Afshin-Majd, Maryam SadeghiNaeeni and Mohammad Mehdi Naghizadeh
Abstract Background: Sulfurmustard(SM) has been used as a chemical warfare agent since the early twentieth century. Despite the large number of studies that have investigated SM induced ocular injuries,few of those studies have also focused on the psychological health status of victims. This study has evaluated the most prominent influences on the psychological health status of patients with severe SM induced ocular injuries.
Methods: This descriptive study was conducted on 149 Iranian war veterans with severe SM induced eye injuries. The psychological health status of all patients was assessed using the Iranian standardized Symptom Check List 90- Revised(SCL90-R) questionnaire.The results of patients’ Global Severity Index (GSI) were compared with the optimal cut-off point of 0.4 that has previously been calculated for GSI in Iranian community.The Mann-Whitney U test, T tests and effect sizes(using Cohen’sd) were employed as statistical methods.Data were analyzed using SPSS software.
Results: The meanage of patients was 44.86(SD=8.7) and mean duration of disease was 21.58(SD=1.20) years. Rate of exposure was on cein99(66.4%) cases. The mean GSI(1.46) of the study group was higher compared to standardized cut off point(0.4) of the Iranian community. The results of this study showed that the mean of total GSI score was higher in participants with lower educational levels (effectsize=0.507), unemployment(effectsize= 0.464) and having more than 3 children(effectsize=0.62). Among the participants, 87(58.4%) cases had a positive psychological history for hospitalization or receiving out patient cares previously and 62(41.6%) cases had a negative psychological history. In addition, the mean of GSI in participants with negative psychological history was lower than those with positive psychological history(MeanChangeDifference=-0.621withSD=0.120). There was a significant difference between positive and negative psychological history with respect to GSI(P<0.001). Conclusion: The study showed that severe ophthalmologic complications in chemical survivors are accompanied with destructive effects on psychological health status. Appropriate management may improve psychological health status in these patients . Keywords: Sulfurmustard,Psychologicalstatus,Ocularcomplication,Warveterans
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